Cyclic AMP (cAMP) is generated by nine membrane-bound adenylyl cyclases (AC1–AC9) and one soluble isoform (sAC). Many drugs target cAMP signalling pathways through their respective G-protein coupled ...
Figure 1: Genetic maps of proximal mouse chromosome 11. The demonstration that the barrelless phenotype results from disruption of adenylyl cyclase type I provides the first evidence that cyclic ...
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