Researchers have simplified the operation of an important class of chemical transformation: synthesis of beta-lactams, the intricate scaffold of many antibiotics. Their experimental protocol minimizes ...

Scientists have developed a new, highly sensitive analytical method that can detect degraded beta-lactam antibacterial agents used in the treatment of bacterial infections. With this method, ...

A carbapenem molecule, a last resort antibiotic, enters the carbapenemase enzyme (blue arrow), where the crucial beta-lactam structure gets broken down. The ineffective molecule then leaves (orange ...

Please provide your email address to receive an email when new articles are posted on . De-escalation of beta-lactam antibiotics was associated with a decreased risk of new resistance among patients ...

Surgical antimicrobial prophylaxis using non-beta‑lactams administered before major surgery was independently associated with a significantly higher risk for surgical site infection than conventional ...