Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria. The ...
Cells that acquire a doubled genome after a failed division step survive and proliferate far more effectively than cells left ...
Eukaryotic cells grow and divide through a specific series of cellular events. These events are tightly controlled, ensuring that the resultant daughter cells are free of DNA errors, and subject to ...
Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many ...
A centromere is a specialized location in the DNA that functions as the control center of cell division and is maintained, unchanged, across generations of cells. It is characterized by a special ...
Yeast’s emergence as a model organism reshaped scientific discovery in cell biology, genetics, and more.
Researchers have found a molecular mechanism that prevents multiplication of potentially dangerous cells by measuring the duration of mitosis. They have shown that this mechanism -- the Mitotic ...
A cell copies all of its DNA, gears up to split in two, and then just… doesn’t. It sits there, swollen with a double genome, and nobody notices. This kind of silent failure has been observed in labs ...
“We closed a gap in our knowledge that was open for 10 years,” says Duccio Conti, a postdoc in the Musacchio group and first author of the publication. In healthy DNA replication, at first, each new ...