CMV seropositivity was assessed by the detection of IgG antibodies to CMV late antigen. All patients and 31 donors (84%) were seropositive for CMV. CMV antigenemia was monitored weekly after ...
New immunotherapies such as adoptive cell transfer, TCR gene therapy and peptide vaccination have the potential to cure human disease in the future. Rosenberg and his colleagues have reported the ...
SAN DIEGO--(BUSINESS WIRE)--BioLegend announces that it has licensed from Sanquin Blood Supply Foundation a novel technology to study antigen-specific T cells. Through a collaborative effort, ...
Our core provides customized MHC/peptide tetramers for identification of antigen-specific T lymphocytes by flow cytometry. Tetramers and/or their derivatives are provided for research purposes only.
An immunological test known as a “tetramer assay” can detect and quantify the T cells in a blood sample that are able to recognize a specific antigen, such as a viral protein. Making the molecular ...
The cost of making a Phycoerythrin conjugated tetramer is $800. The most expensive reagents are the biotin ligase (BirA from Avidity, LLC) and the PE-conjugated streptavidin (Prozyme). On occasion, it ...
MHC tetramers are typically prepared with most of the commonly used fluorescent labels used for flow cytometry. One major advantage of the technique is that the label is already attached to the ...
Phase II Study of Pemetrexed With and Without Folic Acid and Vitamin B12 as Front-Line Therapy in Malignant Pleural Mesothelioma Purpose: To measure the CD8 + T-cell response to a melanoma peptide ...
Protein and peptide microarrays, the emerging tools for proteomics and clinical assays, are high-throughput methods that track binding events and activities, and decide the function of proteins on a ...
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