In drug discovery trials, the potential for a molecule to do harm to an organism must be known accurately. Understanding how a substance under investigation behaves once in the body informs the design ...

When you pop a prescription pill into your mouth, you trust it to address the issue it was meant to fix. But what really happens? How is your body processing the drugs and what happens if the dosage ...

Phase I study to determine the bioavailability and tolerability of a tablet formulation of the PARP inhibitor olaparib in patients with advanced solid tumors: Dose-escalation phase. This is an ASCO ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family ...

Explore our campus, meet lecturers and current students, and learn more about what it's like to study at Manchester. Qualify as a mathematical modeller with key skills in computational approaches in ...