For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Researchers have found that new myelin-making cells are constantly being made in the brain and spinal cord, even in the ...

Researchers at the CiRA Foundation in Kyoto, Japan, have published a detailed study [1] showing how carefully defined culture ...

A team at Johns Hopkins Medicine has focused their work on myelin development using oligodendrocytes to help study conditions like MS.

In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells—one of the few brain cell types that continue to be produced in the adult ...

Our blood consists of many cell types that develop through different stages from a precursor type -- the blood stem cell. An international research team has now investigated the developmental pathways ...

Explore scalable strategies for iPSC-derived islet differentiation using GMP-grade activin A and KGF to advance diabetes therapeutics.

Researchers have developed a way to grow a highly specialized subset of brain nerve cells that are involved in motor neuron ...

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic ...