tRNA is an important component of the biological synthesis of new proteins, as it carries a specific amino acid that will be incorporated to the protein through the ribosome machinery, as directed by ...

Researchers develop a single genome-editing strategy to treat multiple disorders caused by nonsense mutations, promising ...

Loss of TRMT10A led to a decrease in the levels of initiator methionine tRNA (tRNA iMet) and a specific glutamine tRNA (tRNA Gln). This reduction weakened the initiation of protein synthesis for ...

A research paper published in the journal Cell Metabolism by the team of Prof. Liu Qiang at the University of Science and Technology of China (USTC) reveals the critical role of glutamate tRNA ...

The various identities of cells, whether they are in the brain, heart, kidney, or any other tissue, are defined by the genes they expressed. In basic terms, the genes that are active in a cell are ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

A novel tRNA fragment limits UV-driven photoageing by protecting collagen and mRNA stability. Discover the mechanism and its therapeutic potential. Read more.

Meeting with the FDA to review the results from the Phase 3 EFZO-FIT™ study and determine the path forward for efzofitimod in ...

This study reveals that enhancing the activity of a conserved “housekeeping” gene can significantly elevate fruit nutritional and sensory traits. By increasing the expression of a tRNA-associated gene ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...