Tetrabenazine in the treatment of Huntington’s disease - PMC
This review emphasizes the advantage of TBZ over dopamine-depleting compounds used in the treatment of chorea and reveals its clinical efficacy and side effects. Keywords: tetrabenazine, …
Treatment of Chorea in Childhood - Pediatric Neurology
May 23, 2019 · Tetrabenazine (TBZ) was the first dopamine-depleting agent approved by the US Food and Drug Administration (FDA) for the treatment of chorea related to HD. TBZ has a five …
The VMAT-2 inhibitors are utilized for the management of chorea associated with Huntington Disease (HD) and for the management of tardive dyskinesia (TD). Tetrabenazine, the first …
Tetrabenazine: Uses, Dosage, Side Effects, Interactions & more - Drugs.com
Aug 23, 2023 · Tetrabenazine tablets are used to treat involuntary movements (chorea) caused by Huntington's disease, which is a rare, inherited disease that causes nerve cells in the brain …
Tetrabenazine (oral route) - Side effects & dosage - Mayo Clinic
Oct 1, 2025 · Description Tetrabenazine is used to treat chorea (a movement disorder) that is caused by Huntington disease. Tetrabenazine works in the central nervous system (CNS) to …
Huntington Disease and Chorea | Continuum
Tetrabenazine was FDA approved in 2008 for the treatment of chorea in the setting of HD. The TETRA-HD (Efficacy and Safety of Tetrabenazine in Chorea) study demonstrated Class 1 …
Xenazine (Tetrabenazine) - Rare Disease Advisor
Aug 1, 2018 · Xenazine ® (tetrabenazine) is an oral vesicular monoamine transporter 2 (VMAT2) inhibitor that is indicated for the treatment of chorea associated with Huntington disease (HD) …
Tetrabenazine (Xenazine), An FDA-Approved Treatment Option …
Tetrabenazine has been used for decades in several countries to treat chorea and other hyperkinetic movement disorders, such as dystonias and tics. 5 This article provides a concise …
A Choreographed Approach to the Treatment of Chorea
Chorea that interferes with activities of daily living (eg, the ability to dress, eat, chew, or attend to personal hygiene effectively) likely requires treatment. Chorea can cause safety concerns or …
Tetrabenazine as antichorea therapy in Huntington disease | Neurology
Feb 13, 2006 · Abstract Background: Tetrabenazine (TBZ) selectively depletes central monoamines by reversibly binding to the type 2 vesicular monoamine transporter. Open-label …